CHESS human protein structure database

Here we provide open access to 3D protein structure predictions for isoforms of 237,275 human transcripts

Individual predicted structures for CHESS 3 can be found in Isoform Search

Summary tables and all structures can be found in Downloads

Search your own protein structure against our database in Foldseek Search

Sommer M.J. , Cha S. , Varabyou A. , Rincon N. , Park S. , Pertea M., Steinegger M. , Salzberg S.L. - Structure-guided isoform identification for the human transcriptome - eLife 2022